Searchable abstracts of presentations at key conferences in endocrinology

ea0011p434 | Endocrine disruptors | ECE2006

Origin of dysgenetic areas in testes of rats exposed to Di n-butyl phthalate (DBP) during fetal life: A model of human testicular dysgenesis syndrome

Mahood IK , Scott HM , Hallmark N , McKinnell C , Walker M , Fisher JS , Sharpe RM

Disorders of male reproductive health, including testicular cancer, cryptorchidism, hypospadias and low sperm counts, are common and may be increasing in incidence. These conditions manifest at different life stages (low sperm counts and testicular cancer in adulthood; cryptorchidism and hypospadias at birth) but are proposed to originate in fetal life. These disorders have therefore been hypothesized to comprise a ‘testicular dysgenesis syndrome’ (TDS), which result...